Congrats, Chao Xie for being awarded one of the Best Student Poster Presentations in FASEB Science Research Conference (The Biology of Cilia and Flagella) on Aug. 8, 2019 in Snowmass, Colorado. His presentation entitled Olfacotory cilia defects from a single point mutation in BBS1, result in impaired odor detection and perception in a Bardet-Biedl syndrome mouse model, focuses on the use of gene replacement to rescue olfactory dysfunction associated with Bardet-Biedl syndrome (BBS).
Together, our findings demonstrate the penetrance of the BBS1 M390R mutation in OSN cilia and provide a clinically relevant model for the development of gene therapy treatment for congenital ciliopathies in the olfactory systems.
Chao Xie is a Ph.D. student in the Pharmacology concentration of the UF Biomedical Sciences graduate program. Coincidentally, Xie was awarded with a book entitled “Cilia” who’s cover displays an image of olfactory cilia provided by Dr. Jeffrey Martens, Xie’s graduate advisor.